This game is one of my all time favorites. It has a steep learning curve to it, but omg it is so much fun when you get the hang of it. Here is how you can play it on Linux!
1.) Get the Byond client from this link http://www.byond.com/download/build/499/499.1187_byond.exe
2.) Run the installer with wine.
3.) You will need to get mfc42.dll from http://www.dll-files.com/dllindex/dll-files.shtml?mfc42 (click on “DOWNLOAD ZIP-FILE”)
4.) Extract the contents of the mfc42.zip to .wine/drive_c/Program\ Files\ \(x86\)/BYOND/bin
5.) There should be a BYOND icon on your desktop after the install. You can now run it just by double clicking on it.
6.) You will now need to make a BYOND account.
7.) After you register, login, and you can now add locations for Space Station 13
8.) Go to File, and then Open Location.
9.) Add “byond://BYOND.world.1477150822” <– This is the NOX server. One of my Favorites.
10.) Enjoy playing!
I hope this helps out.